The potential of auto-antigen-guided treatment of immune checkpoint inhibitor-mediated myocarditis.
| Publication Type | Comment |
| Authors | Zhu H, Huang Y, Wu S |
| Journal | Med |
| Volume | 4 |
| Issue | 1 |
| Pagination | 13-14 |
| Date Published | 01/13/2023 |
| ISSN | 2666-6340 |
| Keywords | Myocarditis, Antineoplastic Agents, Immunological |
| Abstract | Immune checkpoint inhibitor (ICI)-mediated myocarditis is a rare but devastating side effect of cancer immunotherapy with up to 40% mortality and long-term cardiac issues such as arrhythmias and heart failure in affected patients.1 Recently, Axelrod et al.2 suggested an auto-antigen-driven mechanism as the immunological basis for this disease. |
| DOI | 10.1016/j.medj.2022.12.005 |
| PubMed ID | 36640753 |