Rethinking clinical trials for medical AI with dynamic deployments of adaptive systems.

Publication Type Review
Authors Rosenthal J, Beecy A, Sabuncu M
Journal NPJ Digit Med
Volume 8
Issue 1
Pagination 252
Date Published 05/06/2025
ISSN 2398-6352
Abstract There is a growing recognition of the need for clinical trials to safely and effectively deploy artificial intelligence (AI) in clinical settings. We introduce dynamic deployment as a framework for AI clinical trials tailored for the dynamic nature of large language models, making possible complex medical AI systems which continuously learn and adapt in situ from new data and interactions with users while enabling continuous real-time monitoring and clinical validation.
DOI 10.1038/s41746-025-01674-3
PubMed ID 40328886
PubMed Central ID PMC12056174
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