The Role of Single-Cell Profiling and Deep Immunophenotyping in Understanding Immune Therapy Cardiotoxicity.
| Publication Type | Review |
| Authors | Huang Y, Waliany S, Lee D, Galdos F, Witteles R, Neal J, Fan A, Maecker H, Nguyen P, Wu S, Zhu H |
| Journal | JACC CardioOncol |
| Volume | 4 |
| Issue | 5 |
| Pagination | 629-634 |
| Date Published | 12/20/2022 |
| ISSN | 2666-0873 |
| Abstract | • ICIs used in cancer therapy can cause serious cardiac immune-related side effects. • Single-cell multi-omics are powerful tools in understanding cell subsets/phenotypes. • Multi-omics technology can elucidate disease mechanisms in ICI-induced myocarditis. |
| DOI | 10.1016/j.jaccao.2022.08.012 |
| PubMed ID | 36636436 |
| PubMed Central ID | PMC9830194 |