Using plasma cell-free mRNA to profile immune response and myocardial damage in immune checkpoint inhibitor-induced myocarditis.
| Publication Type | Academic Article |
| Authors | Raissadati A, Zhou X, Chou H, Huang Y, Khatua S, Sun Y, Xu A, Loa S, Hernandez A, Zhu H, Wu S |
| Journal | J Clin Invest |
| Volume | 135 |
| Issue | 16 |
| Date Published | 08/15/2025 |
| ISSN | 1558-8238 |
| Keywords | Myocarditis, Immune Checkpoint Inhibitors, RNA, Messenger, Myocardium, Cell-Free Nucleic Acids |
| Abstract | Plasma cell-free mRNA provides tissue-specific transcriptional profiling, precisely capturing cardiac damage and immune responses in immunotherapy-induced myocarditis. |
| DOI | 10.1172/JCI188817 |
| PubMed ID | 40829177 |
| PubMed Central ID | PMC12352903 |