Viral Teamwork Pushes CRISPR to the Breaking Point.

Publication Type Comment
Authors Nussenzweig P, Marraffini L
Journal Cell
Volume 174
Issue 4
Pagination 772-774
Date Published 08/09/2018
ISSN 1097-4172
Keywords Bacteriophages, Viruses
Abstract Viruses have evolved inhibitors to counteract the CRISPR immune response, but they are not fully potent and need some time to be expressed after the beginning of infection. In this issue of Cell, Borges et al. and Landsberger et al. show that sequential infection gradually immunosuppresses the host to allow effective CRISPR inhibition.
DOI 10.1016/j.cell.2018.07.025
PubMed ID 30096306
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