Domain: Foundational Nutritional Knowledge
Highlight: Metabolism and Nutrition Unit
The Metabolism and Nutrition unit is a 3‑week component of the Essential Principles of Medicine Course. The 3‑week Metabolism and Nutrition unit in the Essential Principles of Medicine course teaches how the body processes macronutrients to produce and regulate energy. Students learn key biochemical pathways, such as glycolysis, the TCA cycle, oxidative phosphorylation, and lipid and amino acid metabolism, and how these are integrated across organs and controlled by hormones like insulin and glucagon.The curriculum emphasizes anabolic and catabolic processes, enzyme regulation, mitochondrial function, and the role of micronutrients, linking core biochemistry to physiological homeostasis. It also connects metabolism to clinical conditions including diabetes, obesity, metabolic syndrome, inborn errors, atherosclerosis, and cancer. Through lectures, problem sets, and assessments, students develop the ability to integrate biochemical mechanisms with disease processes and therapeutic approaches.